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Iris Gratz, PhD

Group Leader WG Gratz

Official position

2014 to present
Group leader for the immunology research group

Scientific team member at the University of California, San Francisco Laboratory: Abul K. Abbas
Research project: Skin immunity in conjunction with new auto-antigens

Scientific team member in the EB House Austria, Laboratory for Molecular Therapy


Research Project

• Immunotolerance in Gene Therapy


Scientific Career

Doctoral studies in Immunology
Position: Scientific team member at the University of Salzburg.
Thesis: A novel intracellular interaction partner of mIgE: HAX-1
Supervisor: Univ. Prof. Dr. Gernot Achatz
Graduation with honours

1995 - 2001
Degree studies Biology/Genetics at the University of Salzburg
Degree thesis: Genetic Immunisation in Allergy Therapy.
Supervisor: Univ. Prof. Dr. Josef Thalhamer
Graduation with honours


Honours and Scholarships

Project funding for the research project: "The Immunology of Type VII Gene Therapy" endowed by the Salzburg Paracelsus Medical University.

Scholarship for clinical and molecular Epidermolysis bullosa research, endowed by the Epidermolysis Bullosa Network.

VWR Dissertation Prize 2007
Bestowed by the Jury of the Austrian Society for Biochemistry and Molecular Biology. International Research Experience

Inducing Immunological Tolerance by means of so-called DEC-205 Targeting.
Dermatology Research Laboratory, headed by Dr. Karsten Mahnke and Prof. A.H. Enk; Department of Dermatology, University Clinics of Heidelberg, Germany.

Eirx Therapeutics Ltd. in Cork / Ireland
DNA Microarray Technology in the Research on Programmed Apoptose


Publications and Lectures for Scientific Congresses

Application of skin antigens fused to a novel single chain fragment specific for murine DEC-205 to induce tolerance in a skin graft model. Annual meeting of the Network of Epidermolysis Bullosa, Freiburg, Germany

HAX-1: An intracellular Interaction Partner of mIgE affecting BCR- Internalization. 32nd FEBS Congress, Vienna, Austria.

Book Chapters

  1. Piñón Hofbauer J, Wally V, Guttmann-Gruber C, Gratz IK, Koller U. Therapy Development for Epidermolysis Bullosa [Online First].  Rare Diseases: Intechopen; 2021.
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