Epidermolysis bullosa simplex (EBS) is an umbrella term for all forms of EB, where blistering occurs within the uppermost layer of skin.
EB Simplex Subtypes
The term "simplex" sometimes makes one tempted to believe that it is "simple" that it refers to uncomplicated and simple forms of EB. That's not quite right. It is true that some forms of EB compared with other forms of EB simplex seem less severe, it means a life can have limitations that can be different or perceived as stressful. There are also some forms of EB simplex, which are very rare, and have very serious effects on the lives and well being among the people affected. It is therefore very important to know the exact diagnosis when EBS is suspected, if you want to adapt to the fucutre course of the disease.
Epidermolysis bullosa simplex (EBS) is the general term for all forms of EB, where blistering takes place within the outer skin/epidermis.
EBS is caused by mutations in different genes.
"Simplex" is not synonymous with "simple".