Research statement
My research focuses on studying the nature of aggressive squamous cell carcinoma which develops especially in patients with recessive dystrophic epidermolysis bullosa. In particular, I am working on the development of an immunetherapy that exploits a pre-existing immunity against common childhood pathogens and redirects it againts tumor cells.
Personal interests
I enjoy being outside in nature, preferably in the mountains. In addition to my scientific education I am a passionate musician and zither player.
Curriculum Vitae Lisa Trattner
Professional career
Since 2021
Scientific Associate at the EB House
Education
Since 2018
Master studies Molecular Medicine, University of Vienna
2018
BSc in Medical and Pharmaceutical Biotechnology, IMC FH Krems
"Investigating the potential use of metformin in the therapy of squamous cell carcinoma in patients with recessive dystrophic epidermolysis bullosa"
Working Group at the EB House: Dr. Josefina Piñón Hofbauer, Dr. Christina Guttmann-Gruber
Additional qualifications
2017 Laboratory Animal Science – Basic Course Rodents (Universität Salzburg)
2020 Laboratory Animal Science – Basic Course Zebrafish (Karolinska Institutet)
Original Articles
- Hainzl S, Trattner L, Liemberger B, Bischof J, Kocher T, Ablinger M, Nyström A, Obermayer A, Klausegger A, Gruber C, Wally V, Bauer JW, Piñón Hofbauer J, Koller U. Splicing Modulation via Antisense Oligonucleotides in Recessive Dystrophic Epidermolysis Bullosa. International Journal of Molecular Sciences 2024.
- Welponer T, Weber DD, Trattner L, Tockner B, Aminzadeh-Gohari S, Leb-Reichl V, Kaufmann A, Zauner R, Wimmer M, Wally V, Felder TK, Strunk D, Koller U, Bauer JW, Kofler B, Guttmann-Gruber C, Piñon Hofbauer J. Metformin shows anti-neoplastic properties by inhibition of oxidative phosphorylation and glycolysis in epidermolysis bullosa-associated aggressive cutaneous squamous cell carcinoma. Journal of the European Academy of Dermatology and Venereology : JEADV 2023
- Woess K, Sun Y, Morio H, Stierschneider A, Kaufmann A, Hainzl S, Trattner L, Kocher T, Tockner B, Leb-Reichl V, Steiner M, Brachtl G, South AP, Bauer JW, Reichelt J, Furihata T, Wally V, Koller U, Piñón Hofbauer J, Guttmann-Gruber C. Evaluating a Targeted Cancer Therapy Approach Mediated by RNA trans-Splicing In Vitro and in a Xenograft Model for Epidermolysis Bullosa-Associated Skin Cancer. International journal of molecular sciences 2022;23.